Prochlorperazine Maleate - Uses, Side Effects, and More

Prochlorperazine Maleate – Uses, Side Effects, and More

Prochlorperazine Maleate – Uses, Side Effects, and More

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This medicine is prescribed to patients experiencing extreme nausea and vomiting as a result of a variety of conditions (for example, after surgery or cancer treatment). In the realm of pharmaceuticals, prochlorperazine is classified as a member of the phenothiazines family. This medicine should not be given to children younger than 2 years old, nor should it be given to children who are due to have surgery.

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Prochlorperazine Maleate: Directions for Use

Take this drug by mouth as advised by your physician, usually three to four times daily. You may take it with or without food.

Your age, current medical condition, and how well you respond to treatment all play a role in determining the appropriate dosage. When treating youngsters, the dosage may also be determined by the child’s weight. You should not take this drug more frequently or increase the dosage that you are now taking it.

If your situation does not improve or if it gets worse, you should consult your doctor.

Side Effects

It is possible for you to have drowsiness, dizziness, lightheadedness, blurred vision, constipation, or dry mouth when taking this medication. Notify your doctor or pharmacist as soon as possible if any of these side effects continue or become worse.

If you suffer from dry mouth, you can alleviate the discomfort by sucking on sugar-free hard candies or ice chips, chewing sugar-free gum, drinking water, or using a saliva substitute.

When rising from a seated or lying position, it is important to do so carefully in order to limit the likelihood of experiencing dizziness and lightheadedness.

Keep in mind that the reason your doctor has recommended that you take this medication is that he or she believes that the potential benefits to you outweigh the potential risks of doing so. The majority of persons who take this medicine do not report experiencing any severe adverse effects.

Notify your physician right away if you experience any serious side effects, such as changes in your mental or emotional state (such as agitation or restlessness), movements that are unusual or uncontrolled (such as a fixed upward stare, neck twisting, tongue movements, or muscle spasms), shaking (tremor), difficulty urinating, enlarged or tender breasts, unusual breast milk production, weakness, easy bleeding or bruising, signs of infection (such as a fever or a persistent sore throat),

In the event that you experience any very significant adverse effects, including seizures, seek immediate medical attention.

This medicine carries a very low risk of causing the neuroleptic malignant syndrome, but there is a chance that it could (NMS). If you develop any of the following symptoms, you should seek immediate medical attention: fever, muscle stiffness/pain/tenderness/weakness, extreme weariness, extreme disorientation, sweating, fast/irregular heartbeat, dark urine, evidence of kidney difficulties (such as a change in the amount of urine).

It is quite unusual for this medicine to cause an extremely severe allergic reaction. However, you should seek immediate medical attention if you detect any symptoms of a significant allergic reaction, such as a rash, itching/swelling (particularly of the face/tongue/throat), extreme dizziness, or difficulty breathing. These symptoms may indicate anaphylaxis.

This list of potential adverse effects is not exhaustive in any way. Please consult your physician or pharmacist if you have any side effects that are not listed above.

In the United States, if you are experiencing any adverse effects, please consult your primary care physician. You can call the FDA at 1-800-FDA-1088 or visit their website at to report any adverse effects.

In Canada, if you are experiencing any adverse effects, please consult your primary care physician. You can call Health Canada at 1-866-234-2345 to report any adverse effects you experience.

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Inform your physician or pharmacist that you are allergic to prochlorperazine, as well as to any other phenothiazines (such as chlorpromazine), or if you have any additional allergies before beginning treatment with prochlorperazine. There is a possibility that this product contains inactive substances, which, if present, could result in allergic responses or other complications. Discuss the matter further with your pharmacist for further information.

Before beginning treatment with this medication, it is important to discuss your medical history with your doctor or pharmacist, particularly if you have a history of any of the following: breathing problems (such as asthma, chronic obstructive pulmonary disease-COPD), blood or immune system disorders (such as bone marrow depression), high pressure in the eye (glaucoma), heart disease (such as irregular heartbeat), liver disease, kidney disease, certain brain disorders (such as Reye’s syndrome, seizures), stomach or

This medication may cause you to feel drowsy, lightheaded, or distort your vision. Drinking alcohol or smoking marijuana (also known as cannabis) can make you feel more lightheaded and sleepy. Do not operate a motor vehicle, any machinery, or engage in any activity that requires alertness or clear vision until you are able to complete them safely. Steer clear of beverages containing alcohol. If you are a marijuana user, you should consult your primary care physician (cannabis).

Before undergoing surgery, it is important to discuss all of the products you use with your dentist or doctor (including prescription drugs, nonprescription drugs, and herbal products).

There is a possibility that using this medication will increase your photosensitivity. Reduce the amount of time you spend in the sun. Stay away from tanning beds and indoor sunlamps. When you go outside, make sure to put on sunscreen and protective gear. If you acquire a sunburn or see any blisters or redness on your skin, make an appointment with your primary care physician as soon as possible.

This prescription may cause you to sweat less, which increases the risk that you will suffer from heat stroke. Stay away from activities that could cause you to overheat, such as working hard or exercising outside while the temperature is high or utilising hot tubs. When the temperature is high, it is important to consume enough of fluids and wear lightweight clothing. In the event that you become overheated, you should immediately look for a place where you can cool off and rest. You should seek immediate medical attention if you develop a fever that does not go away, changes in your mental state or mood, a headache, or dizziness.

It is possible that children are more vulnerable to the adverse effects of this medication, particularly the inability to regulate their movements. When they are ill, they may pose a bigger threat to others (such as having a viral infection, or dehydration).

It is possible that elderly people are more sensitive to the adverse effects of this medication, including low blood pressure, constipation, bladder issues, and nerve and muscle disorders.

During pregnancy, it is important to only use this drug when it is absolutely necessary. Talk to your healthcare provider about the potential drawbacks and advantages. Babies who are born to mothers who have used this medication during the final three months of pregnancy have a very small chance of developing symptoms such as muscle stiffness or shakiness, drowsiness, difficulty feeding or breathing, or continual crying. These symptoms can occur in very rare cases. Inform the physician as soon as possible if you observe any of these symptoms in your infant at any moment throughout the first month of their life.

There is no evidence to suggest that prochlorperazine is found in breast milk. On the other hand, comparable medicines can be found in breast milk. Before starting to breastfeed, you should talk to your healthcare provider.

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Drug interactions can alter the way in which your prescriptions work or raise the likelihood that you will have major adverse effects. This document does not contain all possible medication interactions. Maintain a list of all the goods you use, including prescription and over-the-counter medications, as well as herbal remedies, and give it to both your primary care physician and your pharmacist. Without first seeing your physician, do not begin, stop, or alter the dosage of any medications you are now taking.

Cabergoline, dofetilide, and metoclopramide are a few examples of products that could potentially interact with this medication.

Tell your doctor or pharmacist if you are taking any other products that cause drowsiness, including opioid pain relievers or cough relievers (such as codeine or hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, or zolpidem), muscle relaxants (such as carisoprodol or cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

You should read the labels on all of your medications (such as those meant to treat allergies or coughs and colds) since some of them may contain substances that make you feel sleepy. Talk to your local pharmacist about the proper way to use those products.

This medicine has the potential to skew the findings of some laboratory tests (such as those used to check for phenylketonuria and pregnancy, among others), perhaps leading to inaccurate diagnoses. Ensure that the employees in the laboratory and all of your doctors are aware that you are using this medication.


Dial 911 if you suspect that someone has overdosed and they are exhibiting serious symptoms such as passing out or having problems breathing. In any other case, you should immediately contact a poison control centre. To reach the poison control centre for your area in the United States, dial 1-800-222-1222. Canada residents can call a provincial poison control centre. Changes in mental state or mood (such as agitation or restlessness), extreme sleepiness, convulsions, and an irregular heartbeat are some of the possible symptoms of an overdose.


This drug should not be given to anyone else.

It is possible that you will be subjected to frequent laboratory and/or medical tests in order to monitor your progress or check for any negative effects. Consult your doctor for additional details.

Neglected Dose

If you forget to take a dose, you should take it as soon as you realise you forgot. If it is getting close to the time of the next dose, you should forgo the dose that you missed. Your next dose should be taken at the typical time. It is not necessary to double the dose in order to catch up.


Keep at room temperature and away from light and moisture. Store at room temperature. Keep away from the bathroom at all costs. Always make sure that children and animals are kept well away from any medications.

Unless you have been specifically told to do so, you should not flush drugs down the toilet or pour them down a drain. When it is no longer needed or has passed its expiration date, dispose of this product in the appropriate manner. Talk to your neighbourhood pharmacy or the firm that handles garbage disposal in your area.

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