Ibuprofen and Acetaminophen: What’s the Difference? Can You Take Ibuprofen and Acetaminophen Together?

Ibuprofen and Acetaminophen: What’s the Difference? Can You Take Ibuprofen and Acetaminophen Together?

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Both acetaminophen (Tylenol) and ibuprofen (Advil) are examples of drugs that are available without a prescription and can be purchased without a doctor’s visit to treat pain.

These two drugs represent two distinct classes of analgesics (pain relievers). Ibuprofen is a nonsteroidal anti-inflammatory drug, whereas acetaminophen, which is sometimes labelled as APAP, is its own type of medication (NSAID).

It is generally safe to use acetaminophen and ibuprofen together; however, you will need to pay careful attention to the dosages of both medications that you are administering to yourself.

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How much can I take?

Knowing how much acetaminophen and ibuprofen you are taking at once as well as how often you are taking it is essential to take these medications safely.

Acetaminophen dosage

Acetaminophen can be used in a daily dose of up to 4,000 milligrammes (mg) by anyone who is over the age of 12 and is considered an adult. However, even this low amount is enough to damage the livers of certain people, therefore you should aim for no more than 3,000 mg each day.

It is best to consult with the kid’s healthcare professional to identify the most appropriate and secure dosage for a child’s body weight when the child is younger than 12 years old.

Keep in mind that acetaminophen can be found in a wide range of over-the-counter (OTC) drugs, typically in doses of 325 mg, 500 mg, or 650 mg.

The following are some examples of over-the-counter drugs sold under brand names that might contain acetaminophen:

DayQuil \sDimetapp \sExcedrin \sMidol \sNyQuil \sRobitussin \sSudafed \sTheraflu \sVicks

Keep in mind that if you check at labels, you can also find acetaminophen classified as APAP.

Ibuprofen dosage

Ibuprofen should not be taken in doses that are greater than 1,200 milligrammes in a single day. Pills of 200 milligrammes are a common dosage for over-the-counter ibuprofen. This means that you should take six pills each day. Nevertheless, you should check the quantity of each pill at every opportunity.

Again, it is preferable for parents to consult their child’s healthcare practitioner regarding the most appropriate dosage for their child’s weight.

If you have ibuprofen that requires a prescription, you should discuss the possibility of mixing it with other medications, including acetaminophen, with your doctor before doing so.

The following are the acceptable ranges for adults and children over the age of 12:

3,000 milligrammes of acetaminophen each and every day

Ibuprofen dosage of 1,200 milligrammes per day

If the child is younger than 12 years old, the parent should consult their child’s healthcare professional or the product label for instructions on the appropriate dosage.

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Can I take them at the same time?

Both ibuprofen and acetaminophen can be taken at the same time without any adverse effects. Simply be sure that you do not exceed the dosage that is recommended for you.

When both of these medications are taken at the same time, some individuals report experiencing stomach or abdominal pain. In this particular scenario, it is best to switch around the times that you take each medicine.

For instance, you may start with ibuprofen and then switch to acetaminophen four hours later. After that, you could continue the process as many times as necessary.

There is also the option of alternating the days. If you take ibuprofen on Monday, for instance, you should switch to acetaminophen on Tuesday, and so on and so forth.

Can I mix them with other OTC pain relievers?

A combination of acetaminophen and other nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin or naproxen, is considered to be safe (Aleve). Be sure to adhere to the same recommendations as you would if you were simultaneously taking acetaminophen and ibuprofen.

Ibuprofen, on the other hand, must never be used with any other NSAID. This is due to the fact that all nonsteroidal anti-inflammatory drugs (NSAIDs) use the same mechanisms to reduce pain. You could potentially exacerbate this effect to the point where it becomes dangerous or causes an overdose if you take an increased dose of NSAIDs.

How do I know if I’ve taken too much?

In the event that you have already combined ibuprofen and acetaminophen but are afraid that you may have taken an excessive amount of either prescription, there are a few signs that you will want to keep an eye out for.

After taking ibuprofen and acetaminophen, you should get in touch with your doctor as soon as possible if you develop any of the following symptoms:

tinnitus (ringing in the ears)

heartburn \sconvulsions

feeling queasy and throwing up

sweating stomach pain diarrhoea dizziness

a rash and clouded vision


Pain medications that are available without a prescription include ibuprofen and acetaminophen, respectively. Although it is perfectly safe to take both at the same time, you should make sure that you are not exceeding the amounts that are prescribed for anyone.

If you are taking any other over-the-counter drugs, you should check the labels to ensure that they do not already include acetaminophen.

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