Effexor XR - Uses, Side Effects, Warnings, and More

Effexor XR – Uses, Side Effects, Warnings, and More

Effexor XR – Uses, Side Effects, Warnings, and More

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Depression, anxiety, panic attacks, and social anxiety disorder are some of the conditions that can be treated with venlafaxine (social phobia). It has the potential to improve your mood as well as your energy level, and it may also assist in restoring your interest in day-to-day living. Additionally, it may reduce feelings of dread and anxiety, as well as unpleasant thoughts and the frequency of panic attacks. Inhibitor of both serotonin and norepinephrine reuptake is what venlafaxine is known as (SNRI). It does this by assisting in the process of re-establishing a balance in the brain between two naturally occurring molecules called serotonin and norepinephrine.

Instructions for Using Effexor XR

Before beginning treatment with venlafaxine and whenever you get a refill, make sure you have read the information contained in the Medication Guide and, if it is available, the Patient Information Leaflet that your pharmacist has provided you with. If you have any questions, you should consult with either your physician or your pharmacist.

Take this medication exactly as advised by your physician, which is to say, orally and with a meal once daily, once in the morning and once in the evening.

This drug should not be crushed, chewed, or dissolved in water. This can cause the medicine to be released all at once, which raises the likelihood of experiencing adverse effects. Take the capsule as is, without crushing or chewing it.

If you are going to take the capsules, make sure to swallow them completely. If you have problems swallowing the capsules whole, you can open the capsule and sprinkle the contents into a spoonful of applesauce instead. If you have trouble swallowing the capsules whole, you can open the capsule. Immediately and without chewing, ingest the entirety of the combination. After taking each dose, have a full glass of water.

Your current health status and how well you respond to treatment will determine the appropriate dosage. It is possible that your physician will instruct you to begin treatment with this medicine at a low dose and then gradually increase that dose over the course of a few days. Be sure to pay close attention to the directions that your doctor gives you. It is important to maintain consistent use of this drug in order to get the most out of it. Take it at the same time every day so that you don’t forget when you’re supposed to.

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Continue taking this medication even if you don’t feel like you need it. It is important that you speak with your healthcare provider before discontinuing the use of this medicine. It is possible that certain conditions will become even more severe if you suddenly stop taking this medication. In addition, you can suffer symptoms such as confusion, mood swings, hazy vision, headache, fatigue, changes in the way you sleep, and fleeting sensations that are akin to electric shocks. It is possible that your dose will need to be adjusted gradually in order to lessen the severity of the side effects. Notify your doctor immediately of any symptoms that are new or that have worsened.

It is possible that it will be a few weeks before you notice any positive effects from taking this drug. Notify your primary care physician if your issue persists or worsens.

Adverse Reactions

Please also see the section labeled Warning.

It is possible to experience symptoms such as nausea, drowsiness, dizziness, dry mouth, constipation, lack of appetite, blurred vision, nervousness, difficulty sleeping, irregular perspiration, or yawning while using this medication. Notify your doctor as soon as possible if any of these side effects continue or become worse.

Keep in mind that the reason your doctor has recommended that you take this medication is that he or she believes that the potential benefits to you outweigh the potential risks of doing so. The majority of persons who take this medicine do not report experiencing any severe adverse effects.

It is possible that this drug will cause an increase in your blood pressure. Regularly checking your blood pressure and reporting any excessive readings to your physician is important.

In the event that you have any major adverse effects, including but not limited to: easy bruising or bleeding, decreased interest in sex, changes in sexual ability, muscle cramps or weakness, or shaking, you should contact your doctor as soon as possible (tremor).

If you experience any very serious side effects, such as a cough that won’t go away, shortness of breath, chest pain, a severe or pounding headache, stools that are black or bloody, vomiting that looks like coffee grounds, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night), seizure, or vision changes, get medical help as soon as possible.

This medicine has the potential to raise serotonin levels, as well as the risk of a potentially fatal disease known as serotonin syndrome or poisoning. The danger is increased if you are also taking other medications that boost serotonin levels; thus, you should inform your physician or pharmacist of all the medications you now take (see Drug Interactions section). You should seek immediate medical attention if you have any of the following symptoms: a rapid heartbeat, hallucinations, lack of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation or restlessness.

It is quite unusual for this medicine to cause an extremely severe allergic reaction. However, you should seek immediate medical attention if you detect any symptoms of a significant allergic reaction, such as a rash, itching/swelling (particularly of the face/tongue/throat), extreme dizziness, or difficulty breathing. These symptoms may indicate anaphylaxis.

This list of potential adverse effects is not exhaustive in any way. Please consult your physician or pharmacist if you have any side effects that are not listed above.

In the United States, if you are experiencing any adverse effects, please consult your primary care physician. You can call the FDA at 1-800-FDA-1088 or visit their website at www.fda.gov/medwatch to report any adverse effects.

In Canada, if you are experiencing any adverse effects, please consult your primary care physician. You can call Health Canada at 1-866-234-2345 to report any adverse effects you experience.


Inform your physician or pharmacist that you are allergic to venlafaxine, as well as desvenlafaxine, before beginning treatment with venlafaxine. Also, mention any other allergies you may have. There is a possibility that this product contains inactive substances, which, if present, could result in allergic responses or other complications. Discuss the matter further with your pharmacist for further information.

Before beginning treatment with this medication, it is important to discuss your medical history with your doctor or pharmacist, particularly if you have a history of bleeding disorders, personal or family history of angle-closure type glaucoma, high blood pressure, heart problems (such as heart failure, previous heart attack), high cholesterol, kidney disease, liver disease, seizure disorder, or thyroid disease.

This medication may cause you to feel drowsy, lightheaded, or distort your vision. Drinking alcohol or smoking marijuana (also known as cannabis) can make you feel more lightheaded and sleepy. Do not operate a motor vehicle, or any machinery, or engage in any activity that requires alertness or clear vision until you are able to complete them safely. Steer clear of beverages containing alcohol. If you are a marijuana user, you should consult your primary care physician (cannabis).

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Before undergoing surgery, it is important to discuss all of the products you use with your dentist or doctor (including prescription drugs, nonprescription drugs, and herbal products).

It is possible that older persons will be more sensitive to the adverse effects of this medication, particularly the feeling of vertigo when standing. The risk of developing a type of salt imbalance known as hyponatremia is increased in older persons, particularly among those who take medications known as “water pills” (diuretics). There is a correlation between feeling dizzy and having an imbalance in salt levels. While using this medication, an increased risk of bleeding may also be present for elderly patients.

Loss of appetite and weight loss are two of the potential adverse effects of this medication that could affect children more severely than adults. Keep an eye on the child’s weight and height if they are on this medication.

During pregnancy, it is important to only use this drug when it is absolutely necessary. It could cause harm to an unborn child. In addition, there is a remote possibility that infants whose mothers used this medicine during the last three months of pregnancy will have an increased risk of developing withdrawal symptoms. These symptoms may include trouble eating or breathing, seizures, muscle stiffness, or frequent weeping. Notify the pediatrician as soon as possible if you observe any of these symptoms in your newborn child.

Do not stop taking this drug unless specifically instructed to do so by your doctor; untreated mental and emotional disorders (such as depression, anxiety, and panic attacks) can be a serious conditions if left untreated. Discuss the advantages and risks of using this medicine during pregnancy with your healthcare provider as soon as possible if you are planning a pregnancy, if you get pregnant, or if you have any reason to believe that you may be pregnant.

This medication is excreted into breast milk and may have unintended consequences for an infant who is being breastfed. Before starting to breastfeed, you should talk to your healthcare provider.


Between Drugs Interactions between drugs might alter the way in which your prescriptions work or raise the possibility that you will have major adverse effects. This paper does not include all of the potential medication interactions that could occur. Maintain a list of all the goods you use, including prescription and over-the-counter medications, as well as herbal remedies, and give it to both your primary care physician and your pharmacist. Without first consulting your physician, you should never alter the dosage of any medication, stop taking any medication, or start taking any new medication.

Other medications that have the potential to cause bleeding or bruising (including antiplatelet drugs such as clopidogrel, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen, and “blood thinners” such as dabigatran or warfarin) are examples of products that may have an interaction with this medication.

When used with this drug, the usage of aspirin is associated with an increased risk of bleeding. If, on the other hand, your doctor has instructed you to take low-dose aspirin for the prevention of heart attack or stroke (usually 81-162 milligrams per day), you should keep taking it unless your doctor instructs you otherwise. Low-dose aspirin is typically prescribed in the range of 81-162 milligrams per day. Ask your doctor or pharmacist for more details.

Taking MAO inhibitors in conjunction with this medication may result in severe drug interaction, which could even be fatal. During your course of treatment with this drug, you should refrain from using any MAO inhibitors, including isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine. The majority of MAO inhibitors shouldn’t be used for at least two weeks before therapy with this medicine, and they shouldn’t be taken for at least seven days after treatment. Inquire with your physician regarding the appropriate time to begin or stop using this medicine.

If you are also taking other drugs that enhance serotonin, you put yourself at a greater risk of developing serotonin syndrome or serotonin poisoning. Street drugs such as MDMA or “ecstasy,” the herb St. John’s wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine and other SNRIs such as duloxetine/milnacipran), tryptophan, and a number of other substances are examples of this. When you first begin taking these medications or raise your dosage, you may be putting yourself at a greater risk of developing serotonin syndrome or serotonin poisoning.

Tell your doctor or pharmacist if you are taking any other products that cause drowsiness, including opioid pain relievers or cough relievers (such as codeine or hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, or zolpidem), muscle relaxants (such as carisoprodol or cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

You should read the labels on all of your medications (such as those meant to treat allergies or coughs and colds) since some of them may contain substances that make you feel sleepy. Talk to your local pharmacist about the proper way to use those products.

Desvenlafaxine and venlafaxine share a lot of similarities. While you are using venlafaxine, you should avoid taking any drugs that include desvenlafaxine.

This medicine has the potential to interfere with a variety of laboratory tests, including amphetamine detection urine tests, potentially leading to inaccurate test findings. Ensure that the staff at the lab and all of your physicians are aware that you are using this medication.


Dial 911 if you suspect that someone has overdosed and they are exhibiting serious symptoms such as passing out or having problems breathing. In any other case, you should immediately contact a poison control center. To reach the poison control center for your area in the United States, dial 1-800-222-1222. Canada residents can call a provincial poison control center. Seizures, a rapid or irregular heartbeat, and extreme sleepiness are some of the possible symptoms of an overdose.


This drug should not be given to anyone else.

Always be on time for your scheduled checkups and appointments with the psychiatrist. Tests in the laboratory and/or examinations by a doctor (such as blood pressure and cholesterol levels) should be carried out on a regular basis in order to track your improvement and identify any potential adverse reactions. Consult your doctor for additional details.

Neglected Dose

If you forget to take a dose, you should take it as soon as you realize you forgot. If it is getting close to the time of the next dose, you should forgo the dose that you missed. Your next dose should be taken at the typical time. It is not necessary to double the dose in order to catch up.


Keep at room temperature and away from light and moisture. Store at room temperature. Keep away from the bathroom at all costs. Always make sure that children and animals are kept well away from any medications.

Unless you have been specifically told to do so, you should not flush drugs down the toilet or pour them down a drain. When it is no longer needed or has passed its expiration date, dispose of this product in the appropriate manner. Talk to your neighborhood pharmacy or the firm that handles garbage disposal in your area.

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