Celebrex - Uses, Side Effects, Warnings, and More

Celebrex – Uses, Side Effects, Warnings, and More

Celebrex – Uses, Side Effects, Warnings, and More

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This prescription is classified as a nonsteroidal anti-inflammatory drug (NSAID), more specifically a COX-2 inhibitor, and it reduces both pain and swelling (inflammation). It is effective in treating arthritis, acute pain, as well as the pain and discomfort associated with menstruation. The reduction in pain and swelling that this drug brings about makes it possible for you to engage in more of your regular day-to-day activities.

If you are managing a chronic ailment such as arthritis, you should consult your physician about the possibility of treating your pain with treatments that do not include the use of drugs and/or alternative remedies. Please also see the section labelled Warning. This medicine achieves its effects by inhibiting an enzyme in the body that is responsible for the production of prostaglandins. The reduction of prostaglandins helps to bring about a reduction in both pain and edoema.

How to properly take Celebrex

Before beginning treatment with celecoxib and whenever you get a refill on your prescription, make sure you carefully read the Medication Guide issued by your pharmacist. If you have any questions, you should consult with either your physician or your pharmacist.

Take this drug by mouth exactly as instructed by your physician, which will often be once or twice daily. It is recommended that this medication be consumed with meals because doing so will lower the risk of stomach upset. Your current health status and how well you respond to treatment will determine the appropriate dosage. Take this drug exactly as given, sticking to the smallest effective dose for the shortest amount of time possible (see also Warning section).

Unless your doctor advises you otherwise, take this prescription along with a full glass of water (eight ounces or 240 millilitres total), each time you take it. After taking this medication, remain standing for at least ten minutes before lying down.

It is possible that it will take up to two weeks of taking this medication as directed in order to feel the full benefits of treating certain illnesses (such as arthritis).

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It is important to keep in mind that pain drugs are most effective when they are taken as soon as the first signals of pain appear, even if you are only using this medication “as needed” and not on a regular schedule. It is possible that the medication will not be as effective if you wait until the pain has become more severe before taking it.

Adverse Reactions

Please also see the section labelled Warning.

There is a possibility of stomach distress or flatulence. Notify your healthcare provider or pharmacist as soon as possible if any of these side effects continue or become worse.

Keep in mind that the reason your doctor has recommended that you take this medication is that he or she believes that the potential benefits to you outweigh the potential risks of doing so. The majority of persons who take this medicine do not report experiencing any severe adverse effects.

It is possible that this drug will cause an increase in your blood pressure. Regularly checking your blood pressure and reporting any excessive readings to your physician is important.

Notify your physician as soon as possible if you experience any serious adverse effects, such as a severe headache, pain, swelling, or warmth in the groyne or calf, signs of kidney problems (such as a change in the amount of urine), difficulty swallowing, or symptoms of heart failure (such as swollen ankles or feet, unusual tiredness, and unusual or sudden weight gain).

This medication has a very low risk of causing significant liver disease, but there is a chance that it might be fatal. If you have any symptoms of liver damage, including dark urine, persistent nausea or vomiting, lack of appetite, severe stomach or abdominal pain, or yellowing of the eyes or skin, you should seek immediate medical attention.

It is quite unusual for this medicine to cause an extremely severe allergic reaction. However, you should seek immediate medical attention if you experience any signs of severe allergic response, such as a high temperature, swollen lymph nodes, rash, itching and swelling (particularly of the face, tongue, and neck), severe dizziness, or difficulty breathing.

This list of potential adverse effects is not exhaustive in any way. Please consult your physician or pharmacist if you have any side effects that are not listed above.

In the United States, if you are experiencing any adverse effects, please consult your primary care physician. You can call the FDA at 1-800-FDA-1088 or visit their website at www.fda.gov/medwatch to report any adverse effects.

In Canada, if you are experiencing any adverse effects, please consult your primary care physician. You can call Health Canada at 1-866-234-2345 to report any adverse effects you experience.


Please also see the section labelled Warning.


Inform your physician or pharmacist if you are allergic to aspirin, other NSAIDs (such as ibuprofen), or other COX-2 inhibitors before beginning treatment with celecoxib. You should also make this disclosure if you have any other types of allergies. There is a possibility that this product contains inactive substances, which, if present, could result in allergic responses or other complications. Discuss the matter further with your pharmacist for further information.

Before beginning treatment with this medication, it is important to discuss your medical history with your doctor or pharmacist, particularly if you have a history of any of the following conditions: asthma (including a history of worsening breathing after taking aspirin or other NSAIDs), liver disease, stomach/intestine/oesophagus problems (such as bleeding, ulcers, recurring heartburn), heart disease (such as angina, heart attack), high blood pressure, stroke, blood disorders (such as anaemia, bleeding/ (nasal polyps).

The usage of nonsteroidal anti-inflammatory drugs (NSAIDs), such as celecoxib, has been linked to the development of kidney issues in some patients. It is more probable that you will experience complications if you are dehydrated, if you have heart failure or kidney illness, if you are an older adult, or if you use particular medications (see also Drug Interactions section). In order to avoid becoming dehydrated, it is important to consume a lot of fluids as advised by your physician and to let him or her know straight away if you notice a change in the volume of your urine.

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This medication could cause bleeding in the stomach. Consuming alcohol and tobacco on a regular basis, in particular when coupled with this medication, may put you at an increased risk for bleeding in the stomach. Reduce your intake of alcohol and cigarettes. For further information, please speak with either your physician or pharmacist.

Before undergoing surgery, it is important to discuss all of the products you use with your dentist or doctor (including prescription drugs, nonprescription drugs, and herbal products).

While using this medication, those who are 65 and older may have an increased risk of bleeding in the stomach or intestines, kidney issues, heart attack, and stroke.

When administered to children who have a specific form of arthritis known as systemic onset juvenile rheumatoid arthritis, this medication should be used with extreme caution since these patients may have an elevated risk for very dangerous bleeding or clotting problem (disseminated intravascular coagulation). In the event that your kid experiences abrupt bleeding, bruising, or bluish skin in the fingers or toes, seek immediate medical attention.

Women of reproductive age who are considering utilising this drug should have a discussion with their physician(s) about the potential benefits and drawbacks of doing so first. Inform your primary care physician if you are pregnant or if you want to become pregnant in the near future. It is possible for this drug to cause harm to an unborn child as well as complications with the labour and delivery process. It is strongly discouraged to be used during pregnancy after the 20th week and up to delivery. If your doctor determines that you need to use this drug between the 20th and 30th week of your pregnancy, you should use the smallest effective dose for the shortest amount of time that is safe to do so. After the first 30 weeks of your pregnancy, you should not use this drug.

This drug is found in breast milk after being taken. Consult your physician before beginning to breastfeed your child, even though there have been no reports of any adverse effects on nursing babies.


Between Drugs Interactions between drugs might alter the way in which your prescriptions work or raise the possibility that you will have major adverse effects. This document does not contain all possible medication interactions. Maintain a list of all the goods you use, including prescription and over-the-counter medications, as well as herbal remedies, and give it to both your primary care physician and your pharmacist. Without first consulting your physician, you should never alter the dosage of any medication, stop taking any medication, or start taking any new medication.

Aliskiren, angiotensin-converting enzyme (ACE) inhibitors like captopril and lisinopril, angiotensin II receptor blockers like valsartan and losartan, cidofovir, lithium, and “water pills” are some examples of products that have the potential to interact with this medication (diuretics such as furosemide).

When combined with other medications that also have the potential to cause bleeding, this medication might make the problem much worse. Anti-platelet treatments like clopidogrel and “blood thinners” like dabigatran, enoxaparin, and warfarin are two examples of the types of medications that fall under this category.

It is important to carefully examine the labels of all medications, both those obtained with a prescription and those obtained without one because many medications contain analgesics and antipyretics (aspirin, NSAIDs such as naproxen or ibuprofen). Because of their structural similarity to celecoxib, the combination of these medications may make you more susceptible to experiencing adverse effects.

If, on the other hand, your doctor has instructed you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrammes per day), you should keep taking the aspirin unless your doctor instructs you otherwise. Low-dose aspirin is typically prescribed between 162 and 81 milligrammes per day. Inquire with your primary care physician or your pharmacist for further information.


In this case, an overdose of medication.

Dial 911 if you suspect that someone has overdosed and they are exhibiting serious symptoms such as passing out or having problems breathing. In any other case, you should immediately contact a poison control centre. To reach the poison control centre for your area in the United States, dial 1-800-222-1222. Canada residents can call a provincial poison control centre. Extreme stomach discomfort, vomiting that resembles coffee grounds, a shift in the volume of urine, shallow or sluggish breathing, a severe headache, or loss of consciousness are some of the symptoms that might accompany an overdose.


This drug should not be given to anyone else.

It is possible that you will be subjected to periodic laboratory and/or medical examinations (including testing of your blood pressure, complete blood count, liver function, and kidney function, for example) in order to monitor your progression or check for any adverse effects. Consult your doctor for additional details.

Your flexibility, range of motion, and joint function may all benefit from non-drug treatments for arthritis that have been cleared by your primary care physician. These treatments include losing weight, if necessary, and engaging in strengthening and conditioning activities. Please seek the advice of your physician for further instructions.

Neglected Dose

If you forget to take a dose, you should take it as soon as you realise you forgot. If it is getting close to the time of the next dose, you should forgo the dose that you missed. Your next dose should be taken at the typical time. It is not necessary to double the dose in order to catch up.


Keep at room temperature and away from light and moisture. Store at room temperature. Keep away from the bathroom at all costs. Always make sure that children and animals are kept well away from any medications.

Unless you have been specifically told to do so, you should not flush drugs down the toilet or pour them down a drain. When it is no longer needed or has passed its expiration date, dispose of this product in the appropriate manner. Talk to your neighbourhood pharmacy or the firm that handles garbage disposal in your area.

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