Morphine Oral- Uses, Side Effects, Warnings, and More

Morphine Oral- Uses, Side Effects, Warnings, and More

Morphine Oral- Uses, Side Effects, Warnings, and More

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This drug is prescribed for the purpose of assisting in the relief of severe chronic pain (such as due to cancer). Morphine is an opioid analgesic, which is a class of medications that includes oxycodone and hydrocodone. It functions in the brain to alter how the body perceives and reacts to the sensation of pain. If you have been consistently taking moderate to large dosages of opioid pain medication, then you should only utilise the higher strengths of this drug (90 and 120 mg per capsule). If a person has not been taking opioids on a consistent basis, taking the strength of this medication for the first time could result in an overdose or even death. Do not take the extended-release version of morphine for the treatment of pain that is not severe or that will stop occurring within a few days. The use of this drug “as required” or “sometimes” is not appropriate.

See especially the part labelled “Warning” for instructions on how to use the Morphine SULFATE ER Capsule, Extended Release Multiphase 24 Hour.

Before beginning to use morphine, as well as whenever you get a refill on your prescription, you should read the Medication Guide that your pharmacist has supplied for you. Talk to your primary care physician or pharmacist if you have any concerns or questions.

If your doctor has instructed you to take this medication on a set schedule, you should do so rather than taking it as needed for acute or breakthrough pain. You should take this medication once daily, either with or without food (every 24 hours). If you are experiencing nausea, taking this medication with food may be of assistance. Inquire with your healthcare provider or pharmacist about alternative methods to reduce feelings of sickness (such as lying down for 1 to 2 hours with as little head movement as possible).

Take the capsules with a full glass of water. Adults who have difficulty swallowing the capsule may choose to open the capsule and sprinkle its contents cautiously over a spoonful of soft, chilled applesauce instead of trying to take it whole. Do not chew any of the medicine or meal combinations before consuming it on its whole. After that, give your mouth a quick rinse and then drink the liquid that you used to clean your mouth to double-check that you have taken the correct amount. Chewing the combination or preparing a supply in advance is not recommended. Do not provide this medication to a child in this manner since they may chew the combination and end up taking too much of it. If your kid has difficulty swallowing the capsule, talk to their doctor about switching to an alternative form of morphine.

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Do not administer this drug through a feeding tube because there is a possibility of an overdose.

Your current health status and how well you respond to treatment will determine the appropriate dosage. Do not take the medication in a larger quantity than prescribed, take it more frequently, or take it for a longer period of time than directed. When instructed to do so, withdraw from the drug in the correct manner.

The maximum dose of this drug that is safe to take in a single day is one thousand and six hundred mg. If you take more than the recommended dose of this medication, there is a greater possibility that one of the components will cause harm to your kidneys (fumaric acid).

Before you begin taking this medicine, you should consult with your primary care physician or pharmacist to determine whether or whether you should stop taking your other opioid medication or modify the way you take it (s). It’s possible that your doctor will also recommend other painkillers, including acetaminophen or ibuprofen. Inquire with your healthcare provider or pharmacist about the safe use of morphine in combination with other medications.

It is possible to experience withdrawal symptoms if you suddenly stop using this medicine, particularly if you have been taking it for a long period or in large quantities. Your doctor may carefully reduce your dosage in order to prevent withdrawal symptoms. Notify your healthcare provider or pharmacist as soon as possible if you experience any withdrawal symptoms, including restlessness, mental or mood changes (including anxiety, trouble sleeping, or suicidal thoughts), eyes that water, a runny nose, nausea, diarrhoea, sweating, aching muscles, or sudden changes in behaviour.

It is possible that the effectiveness of this drug will diminish after prolonged use. Talk to your healthcare provider if you notice that this drug is no longer functioning well.

This prescription, despite the fact that it helps a large number of people, can sometimes lead to addiction. If you have a substance use disorder, such as excessive drug or alcohol use or addiction, your risk may be significantly increased for this condition. To reduce the likelihood of becoming addicted to this drug, it should be taken precisely as directed. Inquire with your primary care physician or your pharmacist for further information.

If your pain does not start to improve or if it starts to become worse, you should talk to your doctor.

Side Effects

Please also see the section labelled Warning.

It is possible that this medicine will cause you to experience nausea, vomiting, constipation, lightheadedness, dizziness, or sleepiness. After you have used this drug for a while, you may experience a reduction in the severity of some of these adverse effects. Notify your doctor or pharmacist as soon as possible if any of these side effects continue or become worse.

Eat foods high in dietary fibre, get plenty of exercises, and drink plenty of water to avoid getting constipated. In addition to that, you might need to take a laxative. Inquire with your local pharmacist about the kind of laxative that might work best for you.

When rising from a seated or lying position, it is important to do so carefully in order to limit the likelihood of experiencing dizziness and lightheadedness.

Keep in mind that the reason your doctor has recommended that you take this medication is that he or she believes that the potential benefits to you outweigh the potential risks of doing so. The majority of persons who take this medicine do not report experiencing any severe adverse effects.

Notify your physician as soon as possible if you experience any serious side effects, such as trouble breathing while you are asleep (sleep apnea), changes in your mental state or mood (such as agitation, confusion, or hallucinations), severe stomach or abdominal pain, difficulty urinating, or signs that your adrenal glands are not functioning as effectively as they should be (such as loss of appetite, unusual tiredness, weight loss).

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If you have any very serious adverse effects, such as passing out, having a seizure, breathing too slowly or too shallowly, severe sleepiness or difficulties waking up, get immediate medical attention.

It is quite unusual for this medicine to cause an extremely severe allergic reaction. However, you should seek immediate medical attention if you detect any symptoms of a significant allergic reaction, such as a rash, itching/swelling (particularly of the face/tongue/throat), extreme dizziness, or difficulty breathing. These symptoms may indicate anaphylaxis.

This list of potential adverse effects is not exhaustive in any way. Please consult your physician or pharmacist if you have any side effects that are not listed above.

In the United States, if you are experiencing any adverse effects, please consult your primary care physician. You can call the FDA at 1-800-FDA-1088 or visit their website at to report any adverse effects.

In Canada, if you are experiencing any adverse affects, please consult your primary care physician. You can call Health Canada at 1-866-234-2345 to report any adverse effects you experience.


Tell your doctor or pharmacist if you are allergic to morphine, other opioid pain drugs (like codeine), or if you have any other allergies before you use morphine. If you are allergic to morphine, you may also be allergic to other opioid pain medications. There is a possibility that this product contains inactive substances, which, if present, could result in allergic responses or other complications. Discuss the matter further with your pharmacist for further information.

Before beginning treatment with this medication, it is important to discuss your medical history with your doctor or pharmacist, particularly if you have or have ever had any of the following conditions: conditions affecting the brain (such as a head injury, a tumour, or seizures); breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease-COPD); kidney disease; liver disease; mental or mood disorders (such as confusion or depression); a personal or family history of a substance use disorder

This medication could cause you to feel lightheaded or sleepy. Drinking alcohol or smoking marijuana (also known as cannabis) can make you feel more lightheaded and sleepy. Do not get behind the wheel of a vehicle, operate any machinery, or engage in any activity that requires attentiveness until you are able to do it safely. Steer clear of beverages containing alcohol. If you are a marijuana user, you should consult your primary care physician (cannabis).

Before undergoing surgery, it is important to discuss all of the products you use with your dentist or doctor (including prescription drugs, nonprescription drugs, and herbal products).

Confusion, dizziness, drowsiness, and slow or shallow breathing are some of the potential adverse effects that could be exacerbated in elderly patients by the use of this medication.

During pregnancy, it is important to only use this drug when it is absolutely necessary. It could cause harm to an unborn child. Talk to your healthcare provider about the potential drawbacks and advantages. (Be sure to also check out the Caution section.)

This medication is excreted into breast milk and may have unintended consequences for an infant who is being breastfed. Notify your baby’s doctor as soon as possible if it develops an unusual amount of sleepiness, difficulty eating, or difficulty breathing. Before starting to breastfeed, you should talk to your healthcare provider.


Please also see the section labelled Warning.

Drug interactions can alter the way in which your prescriptions work or raise the likelihood that you will have major adverse effects. This document does not contain all possible medication interactions. Maintain a list of all the goods you use, including prescription and over-the-counter medications, as well as herbal remedies, and give it to both your primary care physician and your pharmacist. Without first consulting your physician, you should never alter the dosage of any medication, stop taking any medication, or start taking any new medication.

Certain pain drugs (mixed opioid agonist-antagonists such as butorphanol, nalbuphine, and pentazocine), naltrexone, products that contain alcohol (such as cough-and-cold syrups), and samidorphan are examples of the types of items that have the potential to interact with this medication.

If this drug is taken with other products that may also cause drowsiness or breathing issues, the chance of serious side effects (such as slow or shallow breathing, severe drowsiness/dizziness) may be increased. These adverse effects include slow or shallow breathing, severe drowsiness/dizziness. Notify your physician or pharmacist if you are taking any other medications, including but not limited to alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines. Other opioid pain relievers or cough suppressants, such as codeine or hydrocodone, are examples of such medications (such as cetirizine, diphenhydramine).

You should read the labels on all of your medications (such as those meant to treat allergies or coughs and colds) since some of them may contain substances that make you feel sleepy. Talk to your local pharmacist about the proper way to use those products.

This medicine has the potential to interfere with a variety of laboratory tests, including those measuring amylase and lipase levels, potentially leading to inaccurate test findings. Ensure that the employees in the laboratory and all of your doctors are aware that you are using this medication.


In this case, an overdose of medication.

If you suspect that someone has overdosed and they are exhibiting serious symptoms such as losing consciousness or having difficulties breathing, give them naloxone if you have it and then phone 911. Call an emergency poison control centre as soon as possible, even if the person is conscious and shows no symptoms. To reach the poison control centre for your area in the United States, dial 1-800-222-1222. Canada residents can call a provincial poison control centre. Coma, shallow or laboured breathing, and a slow heartbeat are all potential symptoms of an overdose.


This drug should not be given to anyone else. It is against the law to give it away.

This drug has been given to you specifically for the treatment of your current condition. Do not use it in the future for the treatment of another condition unless your physician specifically instructs you to do so. In such a circumstance, it’s possible that you’ll need a different drug.

Inquire with your physician or pharmacist about whether or not you should keep naloxone on hand in case of an opioid overdose. Teach members of your household or family the warning signs of an opioid overdose as well as how to treat one if it occurs.

Neglected Dose

If you forget a medication, you should skip the dose you missed. Your next dose should be taken at the typical time. It is not necessary to double the dose in order to catch up.


Keep at room temperature and away from light and moisture. Store at room temperature. Keep away from the bathroom at all costs. Always make sure that children and animals are kept well away from any medications. Please also see the section labelled Warning.

Unless you have been specifically told to do so, you should not flush drugs down the toilet or pour them down a drain. When it is no longer needed or has passed its expiration date, dispose of this product in the appropriate manner. Read the Medication Guide for further information, or speak with your local garbage disposal business or pharmacist for further clarification.

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