Amlodipine Oral Tablet: Side Effects, How to Take, and More

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What is amlodipine oral tablet?

If you have certain diseases that affect your heart, your doctor may recommend that you take amlodipine in the form of an oral tablet.

It is a medication that is available only with a doctor’s prescription and is used to treat high blood pressure in both adults and some children. In adults, it is also employed in the treatment of coronary artery disease (CAD). Angina is a type of chest pain that can be caused when coronary artery disease (CAD) inhibits your arteries from supplying your heart with an adequate amount of blood.

Oral amlodipine tablets are an option for patients who also wish to take additional medications to treat cardiovascular disease and high blood pressure.

See the section titled “What is amlodipine oral tablet used for?” for further information on these conditions and the ways in which amlodipine is used to treat them.

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The fundamentals of amlodipine oral tablets

Amlodipine oral tablet is formulated using amlodipine besylate as the active ingredient. A calcium channel blocker is what medical professionals call this medication.

You are going to take the amlodipine oral tablets through your mouth.

It should be noted that amlodipine is also available as an oral suspension (a type of liquid mixture). However, only the tablet that can be used orally is discussed in this article. Talk to your healthcare provider or pharmacist about the other type of amlodipine if you are interested in learning more about it.

Amlodipine oral tablet formulations under their respective brand names

Generic amlodipine is available in the form of an oral tablet. However, it is also sold under the brand name Norvasc when purchased from a pharmacy.

Take note that another brand-name medicine formulation of amlodipine is available in the oral suspension form. Talk to your healthcare provider or pharmacist about this alternative treatment option to learn more about it.

Because amlodipine oral tablet is a generic drug, we can say that it is an exact replica of the active ingredient found in medication with a brand name. Norvasc is the name of the original prescription medicine that served as the model for amlodipine oral tablets.

It is generally accepted that generic medications are just as safe and effective as the brand-name drug on which they are based. In most cases, the cost of generic pharmaceuticals is significantly lower than that of their brand-name equivalents.

Talk to your healthcare provider about the possibility of switching from oral tablets of amlodipine to the blood pressure medication Norvasc. In addition, check out this article from Healthline to understand more about the distinctions between generic and brand-name medications.

What are amlodipine oral tablets’ negative effects?

The amlodipine oral tablet, like most medications, can have adverse effects that range from moderate to severe. The following lists include descriptions of some of the most frequent adverse effects. These lists do not contain every possible adverse reaction that may occur.

Keep in mind that the following factors can influence the adverse effects of a drug:

your age

the dosage that has been recommended to you

additional conditions that you suffer from

additional pharmaceuticals that you might be taking

More information on the possible adverse effects of the amlodipine oral tablet can be provided to you by your attending physician or pharmacist. They are also able to offer advice on how to lessen the severity of any adverse effects.

Mild side effects

The following is a brief summary of some of the moderate adverse effects that may be caused by the oral tablet form of amlodipine. You can learn about other moderate side effects of taking amlodipine oral tablets by talking to your doctor or pharmacist or reading the prescribed information that comes with the medication.

The following are examples of amlodipine oral tablet adverse effects that are considered to be mild:

anxiety

the ache in the guts

dizziness

erectile dysfunction (ED)

excessive drowsiness or tiredness to an extraordinary degree

fatigue (lack of energy)

clearing out (temporary warmth, redness, or deepening of skin color)

flutterings of the heart (irregular or fast heartbeat)

joint discomfort

a slower pace of heartbeats

difficulties with the muscles, such as stiffness and tremors

nausea

peripheral neuropathy (nerve damage that causes symptoms such as leg pain)

weight gain*

edema (swelling)*

constipation*

The majority of medications have mild adverse effects that, in most cases, disappear after a few days to a couple of weeks. However, if they start to cause you discomfort, you should consult your primary care physician or a pharmacist.

* Please refer to the “Side effect emphasis” section that can be found further down this page for additional information regarding this adverse effect.

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Serious adverse effects may result.

Even though serious adverse reactions to amlodipine oral tablet use are possible, they are relatively uncommon. If the adverse effects are severe, you should contact your physician as soon as possible. However, if you believe that you are experiencing a medical emergency, you should call 911 or the emergency number for your area immediately.

The following are examples of serious adverse events that have been associated with oral amlodipine tablet use:

chest pain caused by angina that is far more severe than typical

assault of the heart

a lowering in the blood pressure

a hypersensitivity reaction*

* Please refer to the “Side effect emphasis” section that can be found further down this page for additional information regarding this adverse effect.

Side effect focus

Gain in weight

While you are using amlodipine oral pills, it is possible that you will gain weight. However, this was not a common adverse effect that researchers saw when testing the medicine.

Edema, often known as swelling, is one of the potential adverse effects of the oral tablet form of amlodipine. If you have edema, you might also put on weight. Please refer to the “Edema, such as leg swelling” section right below for further clarification regarding this matter.

What might be of use?

Have a discussion with your medical professional if you are concerned about putting on weight while taking amlodipine. They can advise you on healthy strategies to keep your weight under control.

Edema, including swelling of the legs

While you are using amlodipine oral pills, you can have swelling, also known as edema. According to the research done on the medicine, this was the adverse effect that occurred the most frequently.

Amlodipine oral pills can cause swelling, most commonly in the hands, feet, arms, and legs. If you take a greater dose of amlodipine, you might be more likely to experience swelling as a side effect of the medication.

What might be of use?

While you are taking amlodipine oral pills, you should let your doctor know about any swelling you experience. They might reduce the dosage that they recommend for you. Alternately, in order to cure your disease, they can decide to move you to a different medication.

It’s possible that your doctor will instruct you to remain taking amlodipine oral tablets as long as your swelling is moderate and doesn’t cause you any discomfort. When combined with this medication, the following home remedies may be of assistance in reducing the amount of swelling experienced:

On the swollen area, you should put on compression stockings or wraps.

Maintain a higher position for the affected region.

Your doctor may recommend that you stop using amlodipine oral pills if your swelling is severe or if it causes you discomfort. If this is the case, your swelling should begin to improve within a few days of discontinuing medication treatment.

Constipation

While you are using amlodipine oral pills, you should be aware that you may get constipation. However, this was not a common adverse effect that researchers saw when testing the medicine.

Symptoms of constipation include, but are not limited to the following:

experiencing a decrease in the typical number of bowel movements

passing hard stools

having bowel movements that take significantly longer than typical

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What might be of use?

While using amlodipine oral pills, you should let your doctor know if you experience any constipation.

If you suffer from constipation, it is essential to maintain proper hydration of the body by consuming a lot of water on a daily basis. You might also try consuming certain meals that are high in water content in order to help you keep hydrated.

Consuming meals that are high in fiber can provide relief from the symptoms of constipation. These foods include raw fruits and vegetables, as well as unprocessed grains.

Medications that are available without a prescription, such as laxatives and stool softeners, can also be helpful in easing the symptoms of constipation. However, before combining amlodipine oral tablets with any new medications, you should make sure to consult with your primary care physician or pharmacist.

A REACTION OF ALLERGIC-TYPE

It’s possible that the oral tablet form of amlodipine will trigger an allergic reaction in certain persons.

The following are examples of symptoms that may accompany a mild allergic reaction:

skin rash

itchiness

clearing out (temporary warmth, redness, or deepening of skin color)

An allergic reaction of a more severe nature is somewhat uncommon but not impossible. A severe allergic response might cause you to experience symptoms such as swelling under your skin, most commonly affecting your eyelids, lips, hands, or feet. Additionally, you may have an enlargement of your tongue, mouth, or throat, which may make it difficult for you to breathe.

If you experience an adverse response after taking an amlodipine oral tablet, you should contact your physician as soon as possible. However, if you believe that you are experiencing a medical emergency, you should call 911 or the emergency number for your area.

How should an oral tablet of Amlodipine be taken?

Your physician will walk you through the proper administration of amlodipine oral pills. In addition to that, they will explain how much medication to take and how frequently. Make sure that you comply with the directions that your doctor gives you. The following are some common dosages, however, it is important to carefully follow the instructions that your physician gives you.

Taking amlodipine oral pill

You are going to take the amlodipine oral tablets through your mouth.

Oral tablets of amlodipine are offered in the following three strengths:

2.5 milligrammes (mg)

5 mg

10 mg

Dosage

There is a wide range of possible dosages for amlodipine, and these ranges change based on the reason that your doctor prescribed the medication to you. Your dosage will also be based on the following factors:

your age, as the dosage that is recommended for you, maybe lower if you are older.

other conditions of your health that you might have.

You will only need to take the oral pills of amlodipine once every day. The medication is not normally administered twice daily.

You are free to administer your dosage at any point during the day. However, the medicine is known to have a number of negative side effects, including severe drowsiness, lethargy, and exhaustion (lack of energy). Therefore, it is recommended that you take your dosage before going to bed.

The maximum daily dose of amlodipine that can be taken in tablet form is 10 milligrams.

Combining the oral tablet form of amlodipine with other medications

It is possible to combine the usage of the oral tablet form of amlodipine with other medications for the treatment of excessive blood pressure, coronary artery disease (CAD), and angina (a type of chest pain).

In combination with the following medications, amlodipine may be used to treat high blood pressure:

inhibitors of angiotensin-converting enzymes, such as the following:

lisinopril (Zestril)

benazepril (Lotensin)

angiotensin II receptor blockers, including but not limited to:

valsartan (Diovan)

losartan (Cozaar)

diuretics that are thiazide-based, such as hydrochlorothiazide (Microzide)

Amlodipine oral tablet may be used in conjunction with the following for the treatment of CAD and angina:

beta-blockers, including the following:

metoprolol (Lopressor)

bisoprolol

nitrates, such as the following:

nitroglycerin (GoNitro)

isosorbide mononitrate (Imdur)

Talk to your physician if you have any concerns or questions regarding additional medications that might be appropriate for treating your condition.

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Concerns about the oral administration of amlodipine tablet

The following is a list of frequently asked questions regarding the use of amlodipine.

What should I do if I forget to take an amlodipine oral tablet dose? If you forget to take your dose of amlodipine, you can take it as soon as you remember. However, if it has been more than 12 hours since you were supposed to take the dose, you should not take it now and instead wait until the next time it is scheduled. If you aren’t sure whether to skip or take a missed dosage of amlodipine oral tablet, talk to your doctor or the pharmacist at the pharmacy where you got it.

Will I need to take the oral tablet form of amlodipine for an extended period of time? Yes, most certainly. If amlodipine is helping you manage your condition and you are not experiencing any intolerable side effects from it, you will most likely continue to take it in the long term. Amlodipine oral pills should be taken according to the instructions provided to you by your physician.

Can an oral tablet of amlodipine be chewed, crushed, or broken up into smaller pieces? The company that makes the amlodipine oral tablet has not disclosed whether or not the medication can be chewed, crushed, or broken up into smaller pieces. Talk to your healthcare provider or pharmacist if you find that you have difficulty swallowing full amlodipine tablets.

Should I take the oral tablet form of amlodipine with or without food? Oral pills of amlodipine can be taken either with food or on an empty stomach.

How long does it take for the oral tablet form of amlodipine to start working? The amlodipine oral pills begin to treat your disease as soon as they are taken into your body. However, it is possible that it will be a few days after you take your first dose before the drug begins to lower your blood pressure or ease the pain in your chest.

QUESTIONS FOR YOUR DOCTOR

It’s possible that you have inquiries regarding the amlodipine oral pill and the treatment strategy that you’re following. It is essential that you share all of your concerns with your treating physician.

The following are some suggestions that may assist direct the course of your conversation:

What effects would taking an oral tablet of amlodipine to have on my body, my mood, and my lifestyle?

If you know that having someone else there will make you feel more at ease, feel free to bring that person along with you to your visit.

If there is something about your diagnosis or treatment that you are unsure of, it is important that you ask your doctor to explain it to you.

Keep in mind that your primary care physician and any other members of the healthcare team are here to assist you. And they want you to have the very best medical care that is available. Therefore, you should not be scared to inquire about your treatment or provide comments on it.

FAQS

What are some other medications that can be taken instead of amlodipine?

High blood pressure, coronary artery disease, and angina are among conditions that can be treated effectively with amlodipine (a type of chest pain). It is classified as a member of a class of medications known as calcium channel blockers.

These disorders can also be treated with a variety of other drugs. The following is a list of possible substitutes for amlodipine:

inhibitors of angiotensin-converting enzymes, such as the following:

lisinopril (Zestril)

benazepril (Lotensin)

angiotensin II receptor blockers, including but not limited to:

valsartan (Diovan)

losartan (Cozaar)

beta-blockers, including the following:

metoprolol (Lopressor)

bisoprolol

medications are known as statins, such as simvastatin (Zocor)

calcium channel blockers, other than amlodipine, including nifedipine, are also an option (Procardia)

Your body will react uniquely to each of the medications described above in order to bring your blood pressure down or improve blood flow to your heart. Talk to your healthcare provider if you have any inquiries regarding the similarities and differences between amlodipine and its equivalents.

Is amlodipine a beta-blocker? Does it also reduce ACE activity? Does it cause diuretic effects?

Amlodipine is not a beta-blocker, an angiotensin-converting enzyme (ACE) inhibitor, or a diuretic, despite what some people may believe.

Calcium channel blockers are a class of medication, and amlodipine is a member of that class. Several other types of medications, including calcium channel blockers, beta-blockers, ACE inhibitors, and diuretics, are used to treat problems that are quite similar. But each substance will affect your body in its own unique way.

Talk to your primary care physician or local pharmacist if you have any inquiries regarding the ways in which amlodipine differs from the aforementioned categories of medications.

When I stop taking amlodipine, would I have any withdrawal symptoms?

When you suddenly stop using amlodipine, you could have certain unpleasant side effects. Your symptoms might change depending on the indication for which you are taking the medication.

Take, for instance:

After discontinuing treatment with amlodipine for hypertension, it is likely that your blood pressure will rise to a higher level than it was before you started taking the drug.

If you have coronary artery disease and angina (a type of chest pain), your doctor may prescribe amlodipine as a treatment. However, if you stop taking the medicine, you may find that your chest pain returns.

Amlodipine should not be discontinued unless specifically instructed to do so by a qualified medical professional. If they advise that you should stop taking amlodipine, it is likely that your physician would lower your dose gradually over the course of some time. This can assist reduce the severity of any adverse effects that you could experience as a result of discontinuing the medicine.

What is the half-life of the drug amlodipine? How long does it remain in your body once you take it?

The amount of time required for half of a given dose of a drug to be eliminated from your body is referred to as the drug’s “half-life.” The half-life of amlodipine ranges from 30 to 50 hours. To put it another way, it takes your body anywhere from 30 to 50 hours to eliminate half of a dose of amlodipine from its system.

A drug will typically be completely eliminated from your system when around five of its half-lives have passed. This indicates that the drug will continue to be present in your system for approximately ten days after the last time you took amlodipine.

Does amlodipine induce hair loss?

Amlodipine will not, in all likelihood, cause you to have a loss of hair. In the studies of medicine, there was no evidence of hair loss.

If you start to notice hair loss while taking amlodipine, make an appointment with your primary care physician. They are able to conduct tests to determine whether this condition is caused by something else.

Will taking amlodipine cause me to have a persistent cough?

No, it is not likely that you may experience a cough when taking amlodipine. Studies conducted on the medicine did not document any adverse effects, including coughing.

However, you may also be taking other medications in conjunction with amlodipine that may cause you to cough. Angiotensin-converting enzyme (ACE) medications, for instance, have been shown to produce coughing in some patients. Lisinopril (brand name: Zestril) and benazepril are both examples of medications known as ACE inhibitors (Lotensin).

Therefore, if you have a cough when using amlodipine in conjunction with these other medications, it is most likely caused by the ACE inhibitor and not by the amlodipine itself.

What should be taken into consideration before taking an oral tablet of amlodipine?

It is essential to have a conversation with your healthcare provider before taking an amlodipine oral tablet. Have a conversation with them about your general health and inform them of any additional health concerns you suffer from.

Before beginning treatment with amlodipine, there are a few things that you need to think about.

Interactions

The interaction of a certain drug with other substances, such as medicines, vaccines, meals, and other substances, might change the way that drug functions. Interactions are the name given to these effects.

Make sure to notify your doctor about any and all drugs you are currently taking, whether they are prescribed or over-the-counter varieties, before beginning treatment with amlodipine oral pills. Also detail any vitamins, herbs, or supplements you consume. If these substances have the potential to interact with amlodipine oral tablets, your healthcare provider or pharmacist will be able to provide you with more information.

Interactions with various pharmaceuticals or dietary supplements

Amlodipine oral tablet has the potential to interact with a number of different classes of medications. Among these medications are:

CYP3A enzyme inhibitors are medications that can be found in your body and hinder its activity.

medicines called cyclosporine (Gengraf) and tacrolimus, both of which inhibit the immune system (Prograf)

The medication sildenafil is used to treat pulmonary arterial hypertension (PAH) as well as erectile dysfunction (ED) (Viagra, Revatio)

The cholesterol-lowering medication known as simvastatin (Zocor), when taken in doses that are higher than 20 mg

This list may not represent all of the possible medication interactions that could occur when using an oral tablet form of amlodipine. Your primary care physician or pharmacist will be able to provide you with additional information regarding these interactions, as well as any others that may occur as a result of your use of the amlodipine oral tablet.

Warnings

If you have certain medical disorders or other circumstances that affect your health, it is possible that the amlodipine oral tablet is not the best treatment option for you. The medical term for conditions that make it unsafe for a person to take a medication is commonly referred to as “contraindications.”

Before you start using amlodipine oral pills, it is important that you discuss your medical history with your doctor. Included in the list of things you need to think about are the following:

Problems with the heart If you have cardiac disorders that involve very narrow heart valves or arteries, you should discuss taking amlodipine oral pills with your doctor before beginning treatment. Aortic stenosis and coronary artery disease with occlusion are two examples of these disorders. After using amlodipine, if you have heart problems like these, you may have a higher chance of experiencing low blood pressure, a heart attack or exacerbated angina (a type of chest pain).

Liver issues. Before beginning treatment with amlodipine oral tablets, you should consult your physician if you have any liver problems, including liver failure. If you have problems with your liver, your body won’t be able to break down amlodipine as efficiently. Therefore, it is likely that your physician would prescribe you a reduced dosage of amlodipine.

Reactions caused by allergies You should not take this medication if you have ever experienced an adverse response to amlodipine oral tablet or to any of the chemicals that it contains. Talk to your healthcare provider about whether there are any other medications that might work better for you.

Use while drinking alcohol.

Consuming alcohol while taking amlodipine oral tablets has not been linked to any negative effects that have been found.

If you use alcohol, you should discuss with your physician the appropriate amount of alcohol consumption that you can have while taking this medication.

Pregnancy and nursing are two different things.

It is not known whether or not it is safe to take amlodipine oral tablets if you are pregnant or breastfeeding.

Talk to your healthcare provider if you are pregnant or if you are planning a pregnancy while you are taking amlodipine. They are able to address the potential dangers as well as the potential benefits of taking amlodipine oral pills while pregnant.

While you are under the influence of amlodipine, it is strongly advised that you do not breastfeed your child. There is currently no information available regarding the nursing implications of the medicine. If you are currently breastfeeding or intend to start breastfeeding, your doctor may recommend an alternative medication to amlodipine for you to take.

What is the function of the amlodipine oral tablet?

If you have certain diseases that affect your heart, your doctor may recommend that you take amlodipine in the form of an oral tablet.

This medication is recommended to treat patients who have high blood pressure. Adults and children older than 6 years are eligible to receive treatment with it for this reason.

Developing hypertension is a process that normally takes place over the course of several years. In most cases, you won’t have any symptoms as a result of it. However, this can cause your heart to pump blood at a higher rate than normal as a result of the increased workload.

However, damage to your blood vessels and organs can occur even in the absence of symptoms if you have high blood pressure. It is especially likely to have an effect on your kidneys, heart, eyes, and brain.

Adults who suffer from coronary artery disease (CAD) may be given an oral tablet form of amlodipine for treatment. A disorder known as coronary artery disease (CAD) is one that causes your blood vessels to constrict, which in turn reduces the amount of blood that flows to your heart. This can result in angina (a type of chest pain).

Oral amlodipine tablets are used to treat the following specific kinds of coronary artery disease (CAD):

angina stabilisation and chronic (long-lasting) duration (a type of chest pain that happens in a predictable pattern)

vasospastic angina (a type of chest pain that happens suddenly)

CAD in the absence of heart failure

The blood flow in the arteries that provide blood to your heart can become reduced due to coronary artery disease (CAD). If this illness is not identified and treated in a timely manner, it can raise your chance of having a heart attack.

Amlodipine oral pills can be taken in combination with other medications for the treatment of both high blood pressure and coronary artery disease (CAD).

Calcium channel blockers are the category of medications that are represented by the amlodipine oral tablet. It works by expanding your blood vessels. This helps lower your blood pressure and improves the blood flow to your heart, both of which contribute to a reduction in the amount of chest pain you experience.

What does an amlodipine oral pill cost?

There are a variety of factors that can influence the price of prescription medications. These considerations include the pharmacies that are covered by your insurance plan and the conditions of your policy. Visit GoodRx.com in order to obtain up-to-date information regarding the cost of an amlodipine oral tablet in your region.

It’s possible that you could qualify for financial aid to help cover the cost of your amlodipine oral tablet purchase. NeedyMeds and Medicine Assistance Tool are two websites that offer resources to assist in lowering the cost of an amlodipine oral tablet.

In addition, they provide you with tools that can assist you in locating educational resources and low-cost medical treatment. Visit their websites if you are interested in learning more.

What measures should be taken in the event of an overdose?

Amlodipine oral pills should not be taken in greater quantities than what is recommended by your physician. When used in amounts greater than this, the potential for adverse consequences increases.

Manifestations of an overdose

One of the symptoms that can be brought on by an overdose is a drop in blood pressure, which can then lead to an increase in heart rate.

What to do in the event that you consume an excessively high dose of amlodipine oral tablet

Please give your healthcare provider a call if you believe you have taken an excessive amount of amlodipine oral tablet. You can also utilise their web resource to contact the American Association of Poison Control Centers, or you can reach them by calling their toll-free number at 800-222-1222. However, if your symptoms are severe, you should phone 911 (or the number for your local emergency services) or go to the nearest emergency room as soon as possible.

What questions to put to your physician

Talk to your primary care physician if you have any concerns or questions regarding the use of amlodipine to treat high blood pressure, coronary artery disease (CAD), or angina (a form of chest pain).

You might want to inquire about the availability of any other treatment choices for these illnesses. The following is a selection of articles that you might find useful:

A Compilation of Medication for Treating High Blood Pressure

Medicine for Treating High Blood Pressure

A Compendium of Medications for Coronary Artery Disease, Also Known as Drugs for CAD

What You Should Be Aware Of Regarding the Treatment of Coronary Artery Disease

In addition, the following is a list of inquiries pertaining to amlodipine oral tablet that you may wish to pose to your primary care physician:

Do any of the foods I eat or the medications I take, such as grapefruit or ibuprofen, react negatively with the amlodipine?

What sets amlodipine apart from other medications used to treat high blood pressure or coronary heart disease?

Should I continue to take other medications to manage my high blood pressure or coronary artery disease while taking amlodipine?