Resveratrol Supplements: Side Effects, Warnings, and Benefits

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Overview

The category of chemicals known as polyphenols includes resveratrol as one of its members. It is believed that they protect the body against damage similar to that which is caused by antioxidants and that this damage can place a person at a higher risk for conditions such as cancer and heart disease.

You can find it in the skin of red grapes, as well as in peanuts, red wine, berries, and a variety of other foods and berries. Red grape skins also contain it.

Supplements containing resveratrol have been sold by several manufacturers in an effort to capitalise on the benefits associated with this compound. Extracts from an Asian plant known as Polygonum cuspidatum can be included in the majority of resveratrol capsules that are sold in the United States. Other types of resveratrol supplements derive their ingredients from extracts of red wine or red grapes.

On the internet, advertisements for these supplements claim a variety of benefits, ranging from weight loss to improved health and longer life.

Do dietary supplements containing resveratrol live up to the claims made about them?

Benefits

Because of the claims that it can slow down the ageing process and fight against disease, it has received a lot of attention. For a long time, scientists have speculated that some compounds found in red wine might offer some health benefits. The decade of the 1990s marked the beginning of the scientific community’s interest in resveratrol, an antioxidant molecule found in red wine. Since then, several antivirals, anti-inflammatory, and anticancer properties of resveratrol have been demonstrated in animal and laboratory research. These results are encouraging.

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It is essential to keep in mind that even though the majority of experts think that it does have potential, there is not yet sufficient data to demonstrate how effectively it works. Supplements containing resveratrol have not been subjected to extensive research on human subjects. We don’t have a good understanding of the potential benefits and drawbacks associated with them. There is also the question of whether or not resveratrol is inherently more significant than some of the other naturally occurring compounds found in wine.

However, preliminary evidence suggests that it may help prevent you from the following:

Diseases of the heart It is believed that it helps reduce inflammation, lowers LDL cholesterol (often known as the “bad” cholesterol), and makes it more difficult for clots to form, all of which can increase the risk of having a heart attack.

Cancer: It has the potential to stop the growth of cancer cells and even stop them from spreading.

Alzheimer’s disease: It may protect nerve cells from injury and prevent the plaque buildup that can lead to the disease.

Resveratrol can help prevent insulin resistance, a disease that can lead to diabetes. Insulin resistance occurs when the body becomes less sensitive to the effects of the hormone insulin, which is responsible for decreasing blood sugar levels. Diabetes mellitus is a potential outcome of the illness.

The SIRT1 gene is thought to be turned on by resveratrol, according to the researchers. It is believed that this gene shields the body from the negative consequences of fat as well as the diseases associated with ageing.

Resveratrol and the Consumption of Red Wine

Because resveratrol may have positive effects on one’s health, some individuals question whether or not they should increase the amount of red wine they consume. However, the majority of experts and organisations like the American Heart Association continue to recommend that people restrict their use of alcoholic beverages to no more than one drink per day for women and no more than two drinks per day for men. A single serving of red wine is equal to four ounces. There is no resveratrol in any of the other kinds of alcohol.

Adverse Reactions

Even when taken in extremely high amounts, research has not uncovered any major side effects associated with resveratrol use. It is generally accepted that consuming resveratrol in the amounts that are naturally present in foods does not pose any health risks. Those who are allergic to grapes or wine could have an adverse reaction to this ingredient.

Resveratrol should not be taken without first consulting a physician by individuals who have preexisting medical issues such as blood disorders.

Before beginning to take resveratrol supplements, you should consult your primary care physician if you are currently using any medications or other supplements on a daily basis. Medications such as blood thinners, blood pressure meds, cancer therapies, MAOI antidepressants, antiviral and antifungal medicines, NSAID painkillers, and supplements such as St. John’s wort, garlic, and ginkgo could have an adverse reaction to them.

Resveratrol is not regulated by the FDA in the same way that other dietary supplements are. Because of this, it is difficult for customers to know exactly what they are purchasing or whether or not the product actually works. There is also no guideline regarding the appropriate dosage, and the amount that you should take per day can differ from one supplement to the next.

The levels of resveratrol found in the majority of dietary supplements are, on average, significantly lower than the amounts that research has shown to be beneficial. Most supplements contain 250 to 500 milligrammes. People would have to take in at least 2,000 milligrammes (two grammes) of resveratrol on a daily basis or more if they wanted to attain the same dose as was employed in some trials. Consult your primary care provider for guidance.

Conclusion

Experts do not recommend taking resveratrol supplements for the prevention of disease or the slowing of the ageing process until more study of a higher quality is conducted. Supplements containing resveratrol are not suggested for use by children, women who are pregnant or breastfeeding, or women who are trying to conceive.