Fluconazole Oral: Uses, Side Effects, Interactions, Pictures & more

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Uses

The antifungal medication fluconazole is employed both for the prevention and treatment of a wide variety of fungal and yeast infections. It is classified as an azole antifungal medication, which is its class name. It achieves its effect by inhibiting the growth of particular strains of fungus.

How to properly administer fluconazole

Before beginning treatment with fluconazole and whenever you get a refill on your prescription, make sure to read the Patient Information Leaflet provided by your pharmacist if one is available. If you have any questions, consult your doctor or pharmacist.

Take this drug exactly as advised by your physician, either with or without meals and in most cases only once per day.

If you are taking this medication in liquid suspension form, shake the bottle very thoroughly just before each dose. Make careful use of a particular instrument or spoon in order to accurately measure the dose. You should not use a regular spoon since you run the risk of not getting the right amount.

Your current health status and how you respond to treatment will determine the appropriate dosage for you. When it comes to children, the dosage is also determined by weight. In most cases, the daily dose for children should not be more than 600 mg unless specifically recommended to do so by a medical professional.

Maintaining a consistent level of the medication in your body is necessary for the medication to perform at its full potential. As prescribed, you should take it at the same time every day.

Even if your symptoms have subsided after a few days, you should keep taking this medication as directed until the complete amount that was recommended has been consumed. If treatment with the medicine is discontinued too soon, the fungus may be able to continue to grow, which could lead to a recurrence of the illness.

If your situation does not improve or if it gets worse, you should consult your physician.

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Side Effects

It is possible that you will experience hair loss, nausea, vomiting, diarrhoea, stomach discomfort or pain, headache, or dizziness. Notify your doctor or pharmacist as soon as possible if any of these side effects continue or become worse.

Keep in mind that the reason your doctor has recommended that you take this medication is that he or she believes that the potential benefits to you outweigh the potential risks of doing so. The majority of persons who take this medicine do not report experiencing any severe adverse effects.

Notify your physician as soon as possible if you experience any severe adverse effects, including symptoms indicating that your adrenal glands are not functioning normally (such as loss of appetite, unusual tiredness, and weight loss).

If you have any side effects that are considered to be very significant, such as a rapid or irregular heartbeat, severe dizziness, or fainting, you should seek immediate medical attention.

This medication has a very low risk of causing significant liver damage. If you begin to experience any symptoms of liver disease, such as severe stomach or abdominal pain, persistent nausea or vomiting, yellowing of the eyes or skin, or black urine, you should seek immediate medical attention.

It is quite unusual for this medicine to cause an extremely severe allergic reaction. However, you should seek immediate medical attention if you experience any symptoms of a serious allergic reaction, such as a fever that does not go away, new or worsening lymph node swelling, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing. These symptoms include: fever that does not go away; new or worsening lymph node swelling; rash; itching/swelling (especially of the face/tongue/

This list of potential adverse effects is not exhaustive in any way. Please consult your physician or pharmacist if you have any side effects that are not listed above.

In the United States, if you are experiencing any adverse effects, please consult your primary care physician. You can call the FDA at 1-800-FDA-1088 or visit their website at www.fda.gov/medwatch to report any adverse effects.

In Canada, if you are experiencing any adverse effects, please consult your primary care physician. You can call Health Canada at 1-866-234-2345 to report any adverse effects you experience.

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Precautions

Inform your physician or pharmacist that you are allergic to fluconazole, as well as to any other azole antifungal medicines (such as ketoconazole or itraconazole), or if you have any additional allergies before beginning treatment with fluconazole. There is a possibility that this product contains inactive substances, which, if present, could result in allergic responses or other complications. Discuss the matter further with your pharmacist for further information.

Before beginning treatment with this drug, it is important to discuss your medical history with your doctor or pharmacist, particularly if you have a history of liver or kidney illness.

Fluconazole has been linked to a disorder that alters the normal beat of the heart (QT prolongation). Rarely, a QT prolongation can produce dangerous (and in extremely rare cases, fatal) fast or irregular heartbeat, in addition to other symptoms (such as severe dizziness and fainting) that require immediate medical attention.

If you have certain medical conditions or are taking other drugs that can cause QT prolongation, your risk of developing the condition may be enhanced. Before beginning treatment with fluconazole, it is important to inform your doctor or pharmacist of all the medications you are currently taking, as well as if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), a family history of certain heart problems, and other similar conditions (QT prolongation in the EKG, sudden cardiac death).

Your chance of having your QT interval becomes prolonged may also be increased if your blood potassium or magnesium levels are low. This risk may be increased if you use certain medications (such as diuretics or “water pills”) or if you have conditions like as intense sweating, diarrhoea, or vomiting. Likewise, this risk may be increased if you use certain drugs. Have a conversation with your healthcare provider about the proper use of fluconazole.

This medicine, despite its rarity, has the possibility of making users feel lightheaded. Alcohol or marijuana (cannabis) can make you dizzier. Do not get behind the wheel of a vehicle, operate any machinery, or engage in any activity that requires attentiveness until you are able to do it safely. Reduce your intake of alcoholic beverages. If you are a marijuana user, you should consult your primary care physician (cannabis).

Before undergoing surgery, it is important to discuss all of the products you use with your dentist or doctor (including prescription drugs, nonprescription drugs, and herbal products).

The adverse effects of this medication, particularly rash, vomiting, diarrhoea, and lengthening of the QT interval, may be felt more acutely by people of advanced age (see above).

During pregnancy, it is important to only use this drug when it is absolutely necessary. If consumed during the first three months of pregnancy, it could potentially cause harm to the unborn child. Inquire about effective methods of birth control to use while taking this medicine and for the subsequent week after therapy has been completed. Before considering this medicine as a treatment for vaginal yeast infections, it is important to first try medications that are applied directly to or around the vagina. Talk to your healthcare provider about the potential drawbacks and advantages.

Fluconazole is excreted into breast milk, although it is highly unlikely that it may affect an infant who is being breastfed. Before starting to breastfeed, you should talk to your healthcare provider.

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Interactions

Drug interactions can alter the way in which your prescriptions work or raise the likelihood that you will have major adverse effects. This document does not contain all possible medication interactions. Maintain a list of all the goods you use, including prescription and over-the-counter medications, as well as herbal remedies, and give it to both your primary care physician and your pharmacist. Without first consulting your physician, you should never alter the dosage of any medication, stop taking any medication, or start taking any new medication.

Clopidogrel is an example of a product that has the potential to interact negatively with this medication.

Pimozide, quinidine, and macrolide antibiotics (such as erythromycin) are just a few of the many medicines that, in addition to fluconazole, have the potential to influence the heart rhythm by prolonging the QT interval.

Fluconazole has the potential to impede the elimination of other drugs from your body, which may have an effect on how well those medications perform. Asunaprevir, flibanserin, lemborexant, lomitapide, and macitentan are some examples of the medications that have been impacted by this issue.

Overdose

Dial 911 if you suspect that someone has overdosed and they are exhibiting serious symptoms such as passing out or having problems breathing. In any other case, you should immediately contact a poison control centre. To reach the poison control centre for your area in the United States, dial 1-800-222-1222. Canadian residents can call a provincial poison control centre. Hallucinations and shifts in the mental and emotional state are two symptoms that may accompany an overdose.

Warnings

This drug should not be given to anyone else.

This drug has been given to you specifically for the treatment of your current condition. If you have another illness in the future, you should not use it unless your doctor tells you to.

Tests in the laboratory and/or examinations by a doctor (such as liver function tests) should be carried out on a regular basis in order to track your improvement and identify any potential adverse reactions. Consult your doctor for additional details.

Neglected Dose

If you forget to take a dose, you should take it as soon as you realise you forgot. If it is getting close to the time of the next dose, you should forgo the dose that you missed. Your next dose should be taken at the typical time. It is not necessary to double the dose in order to catch up.

Storage

Keep the pills at room temperature and protect them from light and moisture by storing them in a dry place. Keep away from the bathroom at all costs.

You can keep the liquid suspension at ambient temperature or in the refrigerator for longer storage. Do not freeze. After 14 days, any medication that has not been used should be thrown away.

Always make sure that children and animals are kept well away from any medications.

Unless you have been specifically told to do so, you should not flush drugs down the toilet or pour them down a drain. When it is no longer needed or has passed its expiration date, dispose of this product in the appropriate manner. Talk to your neighbourhood pharmacy or the firm that handles garbage disposal in your area.