Fish Oil – Uses, Side Effects, Warnings, And More

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Overview

There is a variety of fish that are used to produce fish oil. Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), both of which belong to the omega-3 fatty acid family, is found in high concentrations in it (DHA).

It would appear that the presence of omega-3 fatty acids in fish oil is responsible for its beneficial effects. The mackerel, herring, tuna, and salmon are some examples of fish that are particularly abundant in these oils. Omega-3 fatty acids are not produced in high quantities by the body on their own. In addition to alleviating discomfort and swelling, the anti-clotting properties of omega-3 fatty acids help keep blood from clotting too quickly.

The Food and Drug Administration has given its stamp of approval to some fish oil products for use as over-the-counter and prescription drugs to reduce triglyceride levels. Supplements can also be taken in the form of fish oil. It is not possible to utilise fish oil supplements in place of prescription medications because the supplements do not contain the same quantity of fish oil as the prescription medicines. There is insufficient evidence to support the majority of the purported health benefits of fish oil supplements, including those purportedly beneficial to the heart and the mind.

Fish oil should not be confused with EPA, DHA, cod liver oil, flaxseed oil, krill oil, or shark liver oil. These other oils have completely different functions. Please go to the individual listings for each of these subjects.

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What Are the Benefits and Applications?

efficient in regard to

Triglyceride levels in the blood are significantly higher than normal (hypertriglyceridemia). It is possible to lower extremely high triglyceride levels by taking prescription fish oil medications by mouth. Some of these medications include Lovaza, Omtryg, and Epanova. The daily dosage of these drugs is typically set at 4 grammes in the majority of cases. Although there are fish oil supplements available without a prescription that may also be helpful, the fish oil supplements available without a prescription contain a lower concentration of omega-3 fatty acids. To achieve the same results as taking fish oil as prescribed, individuals would have to take anywhere from six to twelve capsules of fish oil supplements on a regular basis.

Possible Usefulness in Regards to

The process of opening a blood artery that is either obstructed or narrowed (angioplasty). When taken orally for at least three weeks prior to angioplasty and continued for one month following the procedure, fish oil can reduce the rate of blood vessel re-blockage by as much as forty-five per cent.

People who are very unwell often experience an involuntary loss of weight (cachexia or wasting syndrome). It appears that taking a large dose of fish oil by mouth can prevent certain cancer patients from experiencing weight loss. It would appear that doses of fish oil that are too low to have this impact.

Damage was done to the kidneys by the medication cyclosporine. It appears that eating fish oil will prevent those taking cyclosporine from experiencing a renal injury. People who have recently refused a kidney transplant and are on cyclosporine appear to benefit from the use of fish oil in terms of improved kidney function.

Menstrual cramps (dysmenorrhea). Fish oil, whether taken on its own or in combination with vitamin B12 or vitamin E, has been shown to lower the severity of painful periods and the need for pain medication to treat menstrual cramps.

Nausea and vomiting are brought on by an infection of the intestines that has affected the patient. Taking fish oil when pregnant appears to lower the likelihood that the child would have nausea and vomiting as a result of an infection in the intestines.

Heart failure. A reduced incidence of heart failure has been associated with a diet that contains a greater quantity of fish oil from food sources. It is recommended to consume one to two portions of fish that have not been fried once each week. It is still too early to tell whether or not taking fish oil supplements can assist avoid heart failure. People who already have heart failure and take fish oil supplements orally may have a lower risk of passing away or being hospitalised due to their condition.

persons with HIV/AIDS have abnormally high quantities of lipids in their blood. People receiving therapy for HIV/AIDS who have abnormal cholesterol levels as a result of their treatment experience a reduction in their triglyceride levels when they take fish oil supplements orally.

Elevated levels of blood pressure. People who have high blood pressure that ranges from moderate to very high can benefit from taking fish oil in capsule form and consuming it orally. It is not entirely apparent whether or not it benefits persons who already take blood pressure-lowering medication or those who have slightly elevated blood pressure.

A syndrome that, left untreated, might eventually result in renal disease (IgA nephropathy). Patients at high risk for developing IgA nephropathy can experience a reduction in the rate at which they lose kidney function if they take fish oil orally over a period of two to four years. It is unclear whether it is beneficial when used for a very short period of time or in people who are at low risk.

People who drink very little or none at all are more likely to have a buildup of fat in their liver (nonalcoholic fatty liver disease or NAFLD). People who have NAFLD may experience a reduction in liver fat and an improvement in their overall liver health if they consume fish oil orally.

Arthritis rheumatoid of the knee (RA). It has been found that taking fish oil orally, either on its own or in combination with the medicine naproxen, can help relieve RA symptoms. Joint pain and swelling can be alleviated with fish oil administered intravenously, but this treatment must be administered by a medical professional. On the other hand, it does not appear that eating fish oil can prevent RA.

It’s Possible That This Won’t Work for

a degenerative eye condition that is most common in people over the age of 60 (age-related macular degeneration or AMD). People who consume fish on a regular basis, particularly more than once per week, had a lower incidence of age-related eyesight loss. On the other hand, oral consumption of fish oil for a period of up to six years does not prevent or slow down the process of vision loss.

Chest pain (angina). People who have chest pain and take fish oil supplements orally will not see a reduction in their risk of death or an improvement in their heart health.

The narrowing and hardening of the arteries (atherosclerosis). Consuming fish oil through the digestive system does not reduce the progression of atherosclerosis or improve symptoms.

Eczema (atopic dermatitis). Taking supplements of fish oil will not assist in the treatment or prevention of eczema. However, it appears that the risk of eczema is reduced in children between the ages of one and two years old if they consume fish at least once a week.

The abnormal rhythm of the heart (atrial fibrillation). Eating fish high in saturated fat or taking fish oil capsules orally does not lower the chance of having an irregular heartbeat. In point of fact, there is a possibility that the risk of having an irregular heartbeat is enhanced in some persons who use fish oil supplements.

Bipolar disorder. People who suffer from bipolar disorder do not experience an improvement in their symptoms of depression or mania when they take fish oil orally in addition to traditional therapy for the condition.

A respiratory condition that is common in infants and children (bronchopulmonary dysplasia). It does not appear that giving fish oil orally to premature infants will lower the likelihood that the infant will acquire this lung illness.

Problems with the brain’s blood supply on a chronic basis (cerebrovascular diseases). Consuming fish on a regular basis may lower the probability of developing the cerebrovascular illness. On the other hand, consuming fish oil capsules orally does not provide this result.

Skills in both memory and thinking (cognitive function). There is no correlation between orally ingesting fish oil supplements and improved cognitive function in either older adults, young adults, or children.

An infection of the digestive tract that has the potential to cause ulcers (Helicobacter pylori or H. pylori). When compared to conventional treatments, taking fish oil supplements orally does not appear to be effective in reducing the severity of H. pylori infections.

Kidney transplant. After receiving a kidney transplant, taking fish oil in supplement form orally does not help people live longer. Additionally, it does not appear to prevent the body from rejecting the transplant after it has been given.

An ache in the breasts (mastalgia). Consuming fish oil through the digestive system does not appear to alleviate breast pain over the long run.

Multiple sclerosis (MS). People who have multiple sclerosis don’t appear to experience any relief from their symptoms when they consume fish oil.

Osteoarthritis. Oral consumption of fish oil did not result in an improvement in osteoarthritis patients’ levels of pain or function. On the other hand, those who are overweight and suffer from osteoarthritis-like symptoms could benefit from it.

Having a pregnancy complicated by high blood pressure. It would appear that taking fish oil in pill form does not help prevent high blood pressure in pregnant women.

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A condition that can occur during pregnancy and is characterised by elevated blood pressure and the presence of protein in the urine (pre-eclampsia). Consuming fish oil through the digestive system does not appear to prevent pre-eclampsia.

Abnormally fast and irregular heartbeats (ventricular arrhythmias). People who already have abnormally rapid heart rhythms do not have a lower risk of dying if they take fish oil orally since this does not change their chance of developing abnormal heart rhythms.

Diabetes treatment is unlikely to be successful. People with type 2 diabetes who take fish oil supplements orally do not experience a reduction in their blood sugar levels. Additionally, it does not lower the risk of some complications that are associated with diabetes, such as heart attack or stroke. People who have diabetes and who take fish oil orally may have a reduction in the blood fats known as triglycerides.

There is a growing interest in employing fish oil for a variety of additional applications; however, there is insufficient trustworthy data to determine whether or not this could be beneficial.

Adverse Reactions

When consumed via the oral route: When used in dosages of three grammes or less on a daily basis, fish oil is probably safe for the vast majority of people. It is possible that the risk of bleeding will increase if you take more than 3 grammes each day. Heartburn, loose stools, and nosebleeds are some of the negative effects of taking fish oil. These problems can be mitigated to some degree by either freezing fish oil capsules or taking fish oil supplements with meals.

It is possible to do harm to one’s health by ingesting excessive amounts of fish oil obtained from DIETARY sources. There have been reports of mercury and other toxins being found in certain fish. The majority of the time, these compounds are absent from fish oil supplements.

In the event that it is administered to the skin: There is not enough trustworthy information available to determine whether or not fish oil is safe or what the potential adverse effects may be.

Important Safety Instructions and Cautionary Notes

Pregnancy and the act of nursing a baby: When taken orally, fish oil supplements are likely to not cause any adverse effects. It does not appear that the consumption of fish oil during pregnancy has any effect on the developing foetus or on the infant when the mother is nursing. However, pregnant women, women who may become pregnant, breastfeeding mothers, and people who eat shark, swordfish, king mackerel, and tilefish should avoid consuming these types of fish. There is a possibility that these fish have high levels of mercury as well as the presence of other poisons. Reduce your consumption of other types of fish to no more than 12 ounces per week (approximately 3 to 4 servings). It is possible to put your health at risk by eating a lot of fatty fish.

When taken orally, fish oil supplements might not present any health risks to children. Fish oil has been used risk-free in doses as high as approximately 2.2 grammes per day for a period of 12 weeks in adolescents. But youngsters under the age of 10 should never consume more than two ounces of fish in a single week. Large quantities of fish oil derived from DIETARY sources should be avoided because of the potential for health risks. Toxins, including mercury, can be found in fatty fish. Consuming seafood that is polluted on a regular basis has a significant risk of ill effects for children.

Those who suffer from bipolar disorder should be aware that taking fish oil supplements could make some of their symptoms worse.

Liver disease: People who have liver scarring as a result of liver illness may have an increased risk of bleeding if they consume fish oil.

Diabetes: Taking in large amounts of fish oil may make it more difficult to keep a handle on how much sugar is in the blood.

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People who have familial adenomatous polyposis may be at an increased risk of developing cancer if they consume fish oil, according to some research.

A reduced immune system response can be caused by a number of different conditions, including HIV/AIDS. Fish oil, especially in concentrated amounts, has been shown to dampen the body’s immunological response. People whose immune systems are already compromised may experience difficulties as a result of this.

Fish oil may increase the likelihood of patients with implanted defibrillators experiencing an irregular heartbeat. This is because defibrillators are designed to protect patients from experiencing an irregular heartbeat. Fish oil supplements should be avoided in order to err on the side of caution.

Allergic reaction to fish or other seafood Some individuals who are allergic to seafood, such as fish, may also have an allergic reaction to fish oil supplements. There is no research that can be relied on that demonstrates the likelihood that those who are allergic to seafood will have an allergic reaction to fish oil. Patients who are allergic to seafood should be counselled to avoid fish oil supplements or to use them with extreme caution until more is known.

What are the interactions?

Interaction that is Not Overbearing

Take precautions when using these two together.

Antihypertensive medicines, which are prescribed to treat high blood pressure, are known to interact with fish oil.

It’s possible that fish oil can bring down your blood pressure. When used with other medications that lower blood pressure, using fish oil may cause the patient’s blood pressure to drop to an unsafe level. Always keep a tight eye on your blood pressure.

Contraceptive pills, often known as birth control, are known to interact with fish oil.

Triglyceride levels can be lowered with the help of fish oil in some cases. If you take your birth control pill with fish oil, you might experience less of this impact.

Orlistat (Xenical and Alli) has a reaction when used with FISH OIL.

It’s possible that taking orlistat will prevent your body from absorbing the healthy fatty acids that are included in fish oil. It’s possible that separating your doses of fish oil and orlistat by at least two hours will prevent this from happening.

Neoral and Sandimmune’s cyclosporine has been shown to interact with fish oil.

It’s possible that taking fish oil will make your body produce more cyclosporine. Combining cyclosporine with fish oil could potentially increase the drug’s effects as well as its potential negative side effects.

Sirolimus (Rapamune) is known to have an effect when used with FISH OIL.

It’s possible that taking fish oil will raise the amount of sirolimus in your body. It’s possible that this will make sirolimus’ effects and side effects more pronounced.

It has been shown that the drug tacrolimus (Prograf) interacts with fish oil.

It’s possible that taking fish oil will make your body produce more tacrolimus. It’s possible that this will make tacrolimus’ effects and side effects more pronounced.

A Slightly Interacting Party

Take caution when using these two together.

Fish oil has the potential to interact with some medications, including those known as anticoagulants and antiplatelet medicines.

It’s possible that fish oil will prevent blood from clotting. The combination of taking fish oil plus drugs that help reduce blood coagulation may raise the likelihood of experiencing more bruising and bleeding.

The blood thinner Warfarin (Coumadin) is affected by fish oil.

Warfarin is taken to reduce the likelihood of blood clots forming. Additionally, fish oil may make the blood less likely to clot. Taking fish oil in conjunction with warfarin may cause an excessive reduction in the blood’s ability to clot, which in turn raises the risk of bleeding. Use with extreme caution if you are also taking warfarin until further information is available. Regular blood testing is necessary since the prescribed amount of warfarin may need to be adjusted at some point.

Cancer treatments known as platinum agents have been shown to interact with fish oil.

Some products containing fish oil contain a fatty acid that has the potential to lessen the side effects of some chemotherapy medications, which are referred to as platinum agents. However, the quantity of this fatty acid found in the vast majority of fish oil products is most likely insufficient to warrant worry. If you are already taking platinum agents, there is no need for you to discontinue taking fish oil.

Dosing

Adults have been known to take fish oil supplements at dosages of up to 6 grammes per day through oral consumption for a period of up to 12 weeks. Fish oil capsules typically contain between 120 and 375 milligrammes of DHA and between 180 and 465 milligrammes of EPA. There are other prescription medications like Lovaza, Omtryg, and Epanova that contain fish oil as an ingredient. It is not possible to substitute fish oil supplements with fish oil medication that is prescribed by a doctor. Talk to a medical professional to find out which treatment option and dosage would be most appropriate for your particular situation.